3D printed micro-needles to make drug delivery pain-free

New York, Oct 5 (IANS) US researchers have developed a new technique to produce a 3D ‘micro-printed’ array of needles capable of delivering drug without causing any pain, thereby offering a potential alternative to painful injections.

The needles are made from a biomaterial that would degrade in the patient’s body after delivering the drug.

The device could be used in treatments for a wide range of diseases, including skin cancers.

In this study, the researchers reported producing a drug-loaded array for transdermal delivery of a chemotherapeutic drug where the drug is administered through the skin.

The arrays consist of 25 poly (propylene fumarate) microneedles, each needle having a tip and base diametre of 20 micrometre and 200 micrometre, respectively, and a height of one mm.

Constructing the array was challenging, said one of the study authors Jae-Won Choi from University of Akron in Ohio, US.

“3D printing this array was difficult, as the printable biomaterial contains some non-printable solvents and drugs,” Choi noted.

Dacarbazine, commonly used to treat skin cancer, was blended into the solution prior to crosslinking (a final part of the 3D printing process).

The needles were then tested and shown to be able to withstand the stresses and strains they would likely be submitted to when inserted into the body.

“We’d like to have a faster drug release, but this will require more material research. Once we improve this process we can look at developing more controlled drug release,” Choi noted.

“I would hope we will see this being used clinically in five-10 years” he noted.

The results were published in the journal Biofabrication.

Leave a Reply

Please enter your comment!

The opinions, views, and thoughts expressed by the readers and those providing comments are theirs alone and do not reflect the opinions of www.mangalorean.com or any employee thereof. www.mangalorean.com is not responsible for the accuracy of any of the information supplied by the readers. Responsibility for the content of comments belongs to the commenter alone.  

We request the readers to refrain from posting defamatory, inflammatory comments and not indulge in personal attacks. However, it is obligatory on the part of www.mangalorean.com to provide the IP address and other details of senders of such comments to the concerned authorities upon their request.

Hence we request all our readers to help us to delete comments that do not follow these guidelines by informing us at  info@mangalorean.com. Lets work together to keep the comments clean and worthful, thereby make a difference in the community.

Please enter your name here