Chickenpox vaccine may cause eye inflammation

New York, Jan 21 (IANS) Although rare, a vaccine for chickenpox and shingles which has been in use for more than 20 years and is considered an essential medicine by the World Health Organization, can cause corneal inflammation in some patients, says a new study.

The finding suggests that primary care physicians should be aware of possible vision side-effect of the varicella zoster virus vaccine on patients with a history of eye inflammation.

However, the researchers recommended that the majority of patients still be regularly vaccinated against chickenpox and shingles.

“Keratitis, or inflammation of the clear layer on the front of the eye, is a vision issue that can cause serious complications or even permanent damage to your vision if left untreated,” said Frederick Fraunfelder, chair of the department of ophthalmology at University of Missouri School of Medicine in the US.

“By studying case reports from national and international registries, we found at least 20 cases of keratitis occurred in children and adults within a month of administration of the chickenpox and shingles vaccine,” Fraunfelder said.

“While this is a rare occurrence, it is important for physicians to know when giving the vaccine to individuals who have a history of the condition because it could be reactivated by the vaccine,” Fraunfelder noted.

Fraunfelder is the director of the National Registry of Drug-induced Ocular Side Effects, an international effort to gather information on adverse ocular events associated with drugs, chemicals or herbs.

The registry collects data from the US Food and Drug Administration spontaneous reporting database, the WHO spontaneous reporting database and reports from physicians who submit to the registry.

A review of the database and previously published reports found 20 cases of keratitis with a close relationship to administration of the vaccine.

For adults, symptoms of keratitis developed within 24 days of vaccination. For pediatric patients, symptoms of inflammation developed within 14 days.

The study was presented at the 2015 meeting of the American Academy of Ophthalmology in Las Vegas.

Leave a Reply

Please enter your comment!

The opinions, views, and thoughts expressed by the readers and those providing comments are theirs alone and do not reflect the opinions of www.mangalorean.com or any employee thereof. www.mangalorean.com is not responsible for the accuracy of any of the information supplied by the readers. Responsibility for the content of comments belongs to the commenter alone.  

We request the readers to refrain from posting defamatory, inflammatory comments and not indulge in personal attacks. However, it is obligatory on the part of www.mangalorean.com to provide the IP address and other details of senders of such comments to the concerned authorities upon their request.

Hence we request all our readers to help us to delete comments that do not follow these guidelines by informing us at  info@mangalorean.com. Lets work together to keep the comments clean and worthful, thereby make a difference in the community.

Please enter your name here