DNA repair method prevents disease

Moscow, July 4 (IANS) A team of Russian researchers has discovered a mechanism of DNA repair that will help prevent and treat diseases in the future.

The DNA molecule is chemically unstable, giving rise to DNA lesions of different nature.

That is why DNA damage detection, signalling and repair are needed.

The damage of the DNA, if not repaired, leads to accumulation of mutations, cell death and to the development of various diseases, including Alzheimer’s.

“We have shown, not yet in the cell but in vitro, that the repair of breaks in the other DNA chain, which is “hidden” in the nucleosome, is still possible,” said Vasily M Studitsky, professor at Lomonosov Moscow State University.

In higher organisms, DNA is bound with proteins in complexes called the nucleosome.

The mechanism of DNA repair opens up new perspectives for the treatment and prevention of neurodegenerative diseases.

The article was published in the journal Science Advances.


Leave a Reply

Please enter your comment!

The opinions, views, and thoughts expressed by the readers and those providing comments are theirs alone and do not reflect the opinions of www.mangalorean.com or any employee thereof. www.mangalorean.com is not responsible for the accuracy of any of the information supplied by the readers. Responsibility for the content of comments belongs to the commenter alone.  

We request the readers to refrain from posting defamatory, inflammatory comments and not indulge in personal attacks. However, it is obligatory on the part of www.mangalorean.com to provide the IP address and other details of senders of such comments to the concerned authorities upon their request.

Hence we request all our readers to help us to delete comments that do not follow these guidelines by informing us at  info@mangalorean.com. Lets work together to keep the comments clean and worthful, thereby make a difference in the community.

Please enter your name here