Genetic mutations clue to breast cancer relapse

Vienna, Sep 26 (IANS) A British research team has found genetic mutations as clues to breast cancer relapse, saying these could tell whether breast cancer is likely to relapse after treatment.

The research was presented at the European Cancer Congress (ECC) here on Friday by Dr Lucy Yates, leader of the team from the Wellcome Trust Sanger Institute at the University of Cambridge, Xinhua news agency reported.

While most breast cancer patients are able to be successfully treated, about one in five will see a relapse of the disease following treatment.

The team has studied 1,000 women with breast cancer including 161 cases of relapse. It compared primary and secondary cancers and found noticeable genetic differences and mutations in secondary cancers, which were relatively uncommon in those appearing for the first time.

Yates said patterns found show that some primary cancers appear to show a predisposition toward a relapse and are potential targets for therapies which include taking regular tissue samples from cancers to show changes in the progression of the disease and to target its particular genetic mutation.

New developments mean this can also be analysed via blood samples, on which it is much simpler to conduct tissue biopsies, Yates said.

The team hopes that likelihood of a relapse will be determined upon diagnosis of an individual case, and a personalised therapy will then be offered to prevent it, he added.

Leave a Reply

Please enter your comment!

The opinions, views, and thoughts expressed by the readers and those providing comments are theirs alone and do not reflect the opinions of or any employee thereof. is not responsible for the accuracy of any of the information supplied by the readers. Responsibility for the content of comments belongs to the commenter alone.  

We request the readers to refrain from posting defamatory, inflammatory comments and not indulge in personal attacks. However, it is obligatory on the part of to provide the IP address and other details of senders of such comments to the concerned authorities upon their request.

Hence we request all our readers to help us to delete comments that do not follow these guidelines by informing us at Lets work together to keep the comments clean and worthful, thereby make a difference in the community.

Please enter your name here