Fasting-mimicking diet can treat inflammatory bowel disease: Study

Spread the love

Fasting-mimicking diet can treat inflammatory bowel disease: Study

New York: Eating a low calorie diet that mimics fasting can help reduce intestinal inflammation and repair the gut and help treat inflammatory bowel disease (IBD).

Researchers from the University of Southern California found that a “fasting-mimicking diet” caused a reduction in intestinal inflammation and an increase in intestinal stem cells in part by promoting the expansion of beneficial gut microbiota.

Multiple cycles of the fasting-mimicking diet activated stem cells and led to a regenerative effort in the colon and the small intestine.

Fasting primes the body for improvement, but it is the “re-feeding” that provides the opportunity to rebuild cells and tissues, the researchers said.

“The study determined that the dietary components are contributing to the beneficial effects, it’s not just about the cells of the human body but it’s also about the microbes that are affected by both the fasting and the diet,” said Valter Longo, Professor at the varsity.

“The ingredients in the diet pushed the microbes to help the fasting maximise the benefits against IBD,” he added.

For the study, published in Cell Reports journal, the team carried out clinical trials where one group of mice consumed a four-day fasting-mimicking diet, an approximate 50 per cent of their normal caloric intake on the first day and 10 per cent of their normal caloric intake from the second through fourth days.

While, another group adhered to fasting with a water-only diet for two days.

The findings showed that two cycles of a four-day fasting-mimicking diet followed by a normal diet “appeared to be enough to mitigate some, and reverse other, IBD-associated symptoms”.

Whereas, water-only fasting indicated that certain nutrients in the fasting-mimicking diet contribute to the microbial and anti-inflammatory changes necessary to “maximise the benefits against IBD”, Longo said.

Spread the love

Leave a Reply

Please enter your comment!

The opinions, views, and thoughts expressed by the readers and those providing comments are theirs alone and do not reflect the opinions of or any employee thereof. is not responsible for the accuracy of any of the information supplied by the readers. Responsibility for the content of comments belongs to the commenter alone.  

We request the readers to refrain from posting defamatory, inflammatory comments and not indulge in personal attacks. However, it is obligatory on the part of to provide the IP address and other details of senders of such comments to the concerned authorities upon their request.

Hence we request all our readers to help us to delete comments that do not follow these guidelines by informing us at Lets work together to keep the comments clean and worthful, thereby make a difference in the community.

Please enter your name here