New drug may treat both diabetes and bone loss

New drug may treat both diabetes and bone loss

New York, July 28 (IANS) Researchers have developed a new class of compound that has shown promise in treating both diabetes and bone disease.

In addition to its more obvious ills, Type-2 diabetes is a condition closely associated with bone fractures, increasing the risk of fractures twofold. To make matters worse, certain anti-diabetic drugs further increase this risk, particularly in postmenopausal women, severely limiting their treatment options.

But the new dual-targeting drug candidate, referenced as “SR10171.”, could treat both diabetes and bone disease.

“SR10171 improves bone mass regardless of body mass index, normal to obese,” said co-lead researcher Patrick Griffin, professor at the Florida campus of The Scripps Research Institute (TSRI) in the US.

“So you could use such a drug to treat osteoporosis whether patients are diabetic or not,” Griffin added.

The drug increases bone mass by expanding bone formation (deposition of new bone) and bone turnover (a normal process of replacement of old bone).

A proper balance of these two processes is critical to healthy bone maintenance, and this balance is frequently negatively affected in diabetic patients.

In animal models treated with the compound, fat formation in the bone marrow was successfully blocked independent of their metabolic state (healthy or diabetic), showed the study published online in the journal EbioMedicine.

Leave a Reply

Please enter your comment!

The opinions, views, and thoughts expressed by the readers and those providing comments are theirs alone and do not reflect the opinions of or any employee thereof. is not responsible for the accuracy of any of the information supplied by the readers. Responsibility for the content of comments belongs to the commenter alone.  

We request the readers to refrain from posting defamatory, inflammatory comments and not indulge in personal attacks. However, it is obligatory on the part of to provide the IP address and other details of senders of such comments to the concerned authorities upon their request.

Hence we request all our readers to help us to delete comments that do not follow these guidelines by informing us at Lets work together to keep the comments clean and worthful, thereby make a difference in the community.

Please enter your name here