New drug to beat brain and breast cancers

New York, July 16 (IANS) Researchers have discovered two chemical compounds that effectively stop the growth of brain cancer cells and breast tumours, opening the way for potential new drugs to be developed.

“It is particularly encouraging for brain tumour patients, who do not currently have effective treatment options besides surgery,” said James Turkson from University of Hawaii Cancer Centre in the US.

“The targeted treatments are less toxic and therefore will give cancer patients a better quality of life when both compounds are developed as drugs,” Turkson said.

In the study published in the journal Cancer Research, the researchers examined compounds that inhibit Stat3, a protein implicated in a variety of cancers that include brain and breast cancers.

In mouse models of brain and breast cancer, the two compounds effectively inhibited tumour growth, the results said.

The two chemical compounds, a hydroxamic acid-based inhibitor (SH5-07), and a benzoic acid-based inhibitor (SH4-54) designed at the UH Cancer Center stopped the growth of brain and breast cancer cells by blocking a certain function of the Stat3 protein.

The two compounds stop the protein from promoting cancer cells to grow, thus stopping the tumours from growing.

“Our results offer preclinical proof of concept for SH5-07 and SH4-54 as candidates for further development as cancer therapeutics,” the study said.

Leave a Reply

Please enter your comment!

The opinions, views, and thoughts expressed by the readers and those providing comments are theirs alone and do not reflect the opinions of or any employee thereof. is not responsible for the accuracy of any of the information supplied by the readers. Responsibility for the content of comments belongs to the commenter alone.  

We request the readers to refrain from posting defamatory, inflammatory comments and not indulge in personal attacks. However, it is obligatory on the part of to provide the IP address and other details of senders of such comments to the concerned authorities upon their request.

Hence we request all our readers to help us to delete comments that do not follow these guidelines by informing us at Lets work together to keep the comments clean and worthful, thereby make a difference in the community.

Please enter your name here